Micro- and nano-fluidics have already become the hotspot and front of current research since the mission of modern technology is miniaturization, integration, and precision. Notably, the micro- and nano dimensions that quell the inertial nonlinearity bring boundary effects and coupling effects of multiscale and multiple physical fields, less remarkable on our macroscale, to prominence. Accordingly, counterintuitive phenomena keep emerging from micro- and nano-scale fluid systems. The research on micro- and nano-flows focuses on exploring new physics behind the phenomena and creating innovative technologies. To achieve these goals, we take advantage of many state-of-the-art tools and techniques, including but not limited to micro-and nano-fabrication systems, ion transport devices, flow visualization and measurements, interfacial properties modification, and microfluidic techniques. The expected outcomes of these studies have applications in diverse fields, including advanced health and medical device design, space equipment manufacturing, biological testing, advanced material fabrication, desalination, and so on.